Nonselective beta-blockers in primary prophylaxis of esophageal variceal bleeding in patients with ascites waitlisted for liver transplantation

Objective: to determine the efficacy of non-selective beta-blockers (NSBBs) in primary prevention bleeding esophageal varices and assess their impact on survival patients with ascites enrolled liver transplant waiting list (LTWL). Materials methods . We carried out a retrospective comparative study cirrhotic severe without before enrollment LTWL. Primary prophylaxis variceal included use NSBBs (n = 97, group 1). These drugs were not used other 91, 2). Results There no significant differences between groups terms clinical, laboratory demographic parameters, MELD scores Child-Turcotte-Pugh (CTP) classes for cirrhosis. Patient had respect incidence medium- large-sized ascites. Bleeding was significantly lower than non-NSBBs (52.6% 95.6%, respectively, p 0.0001). Conclusion constitute an efficacious therapy bleeding, thereby saving life preventing delisting from